WebCamptothecin, Camptotheca acuminata A cell-permeable DNA topoisomerase I inhibitor.; CAS Number: 7689-03-4; Synonyms: Camptothecin, Camptotheca acuminata,4-Ethyl-4-hydroxy-1H-pyrano[3ʹ,4ʹ:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione; find Sigma-Aldrich-208925 MSDS, related peer-reviewed papers, technical documents, similar … WebThe meaning of CAMPTOTHECIN is an alkaloid C20H16N2O4 from the wood of a Chinese tree (Camptotheca acuminata of the family Nyssaceae) that has shown some …
Camptothecin C20H16N2O4 - PubChem
WebMin: 1. Step: 1. Add to Cart. TG2011-4. Topoisomerase I Western Blot Marker. The Western blot marker set for topo I is used to unambiguously locate the position of the 100 kDa form of intact topo I. This product is supplied in SDS-PAGE loading buffer and ready to load directly onto an SDS-PAGE. $ 375.00. Max: WebApr 13, 2024 · The fabrication of pH-sensitive lignin-based materials has received considerable attention in various fields, such as biomass refining, pharmaceuticals, and detecting techniques. However, the pH-sensitive mechanism of these materials is usually depending on the hydroxyl or carboxyl content in the lignin structure, which hinders the … great eastern hospitalisation claim
Camptothecin Supplier CAS 7689-03-4 Tocris Bioscience
WebCamptothecin traps an important cellular enzyme, topoisomerase I, in complexes with DNA. This prevents cancer cell DNA replication and results in the death of the cancer cell. This unique mode of action rekindled interest in developing analogs of camptothecin that were both water soluble and retained anticancer activity. WebCamptothecin is an alkaloid first isolated from the stem wood of the tree Camptotheca acuminata (Nyssaceae), and has potent antitumor activity. 31 Camptothecin acts by inhibiting the enzyme topoisomerase-I, which is responsible for relaxing supercoils that are generated during transcription and DNA replication. 32 A number of reports have ... great eastern hospital panel