High intensity statin bnf
Web26 de fev. de 2024 · Based on high-quality evidence from randomized controlled trials (RCTs), high-intensity statin therapy should be instituted with a goal of lowering LDL-C levels by 50% or more in patients... Web18 de jul. de 2014 · This guideline covers the assessment and care of adults who are at risk of or who have cardiovascular disease (CVD), such as heart disease and stroke. It aims to help healthcare professionals identify people who are at risk of cardiovascular problems including people with type 1 or type 2 diabetes, or chronic kidney disease. It describes …
High intensity statin bnf
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WebBefore starting treatment with statins, at least one full lipid profile (non-fasting) should be measured, including total cholesterol, HDL-cholesterol, non-HDL-cholesterol (calculated … Webinjury after initiation of high-intensity statin [18,19], rais-ing concern for worsening kidney function in patients with CKD and long-term use of high-intensity statin. It is well-known that statin therapy in patients with CKD is not as effective as in people without CKD. The reason for this is not clear, but we hypothesized that statin intensity
WebPrescribing lipid-modification therapy (high-intensity statin or ezetimibe) to achieve a target reduction in LDL cholesterol concentration of greater than 50% from baseline. Considering the need for antihypertensive treatment in people with hypertension, and the need for aspirin for the primary prevention of CVD. Web27 de ago. de 2008 · 1.3.1.11 Healthcare professionals should offer adults with FH a referral to a specialist with expertise in FH if treatment with the maximum tolerated dose of a high-intensity statin and ezetimibe does not achieve a recommended reduction in LDL‑C concentration of greater than 50% from baseline (that is, LDL‑C concentration before …
WebStatins also increase concentrations of HDL-cholesterol. Statins reduce cardiovascular disease events and total mortality in adults, irrespective of the initial cholesterol concentration. They are the drugs of first choice in children and are generally well tolerated; atorvastatin and simvastatin are the preferred statins. Web31 de mar. de 2015 · Researchers conducted three trials of high intensity-statins that show “high-intensity statins reduce events more than moderate-intensity statins. That’s why …
Web11 de abr. de 2024 · Women were less likely to be prescribed a high-intensity statin than men (41.4% vs 49.8%, p <0.001, OR: 0.71 with 95% CI 0.68-0.73; Figures 2 and 3). Similar to rates of statin prescription overall, sex differences in the prescription of high-intensity statins were present in all subgroups (Figure 5). Download : Download high-res image …
WebIf QRISK ≥10%: after addressing modifiable risk factors and following a shared decision: consider initiating statin therapy with a moderate dose of a high intensity drug (HI): atorvastatin 20mg daily ( alternative is rosuvastatin 10mg daily ) - see page 6 for high intensity statin comparison table - consider drug interactions that may affect dosing … philips healthcare best the netherlandsWeb2 de mai. de 2024 · Lamprecht D.G., Shaw P.B., King J.B., Hogan K.N., Olson K.L. "Trends in high-intensity statin use and low-density lipoprotein cholesterol control among patients enrolled in a clinical pharmacy cardiac risk service". J Clin Lipidol 2024;12:999-1007. Crossref Medline Google Scholar; 10. truth oneWeb2. Statin therapy has shown clear benefits and is recommended in four major groups of patients (strong evidence): 1,2. Patient Group Recommended Intensity of Statin Treatment Clinical ASCVD* Age ≤ 75 years with no statin-related safety concerns † a High Age > 75 years or with statin-related safety concerns Moderate . LDL . ≥ 190 mg/dL ... philips healthcare best netherlandsWebThe guideline identifies high- and moderate-intensity statin therapy for use in primary and secondary prevention . Less evidence is available to support nonstatin therapy for … philips healthcare benefitsWeb8 de mai. de 2012 · Two large prospective randomized studies, the Heart Protection Study (simvastatin at 40 mg/day) and Stroke Prevention by Aggressive Cholesterol Reduction … philips healthcare careers canadaWeb2 de mai. de 2024 · Of the 601,934 patients with established ASCVD, 41.7% were female, and the mean age was 67.5 ± 13.3 years. Overall, 22.5% of the cohort were on a high-intensity statin, 27.6% were on a low- or moderate-intensity statin, and 49.9% were not on any statin. In multivariable analysis, younger patients, female patients, and those with … truth on firephilips healthcare blumenau