Rbm38 in cancer: role and mechanism
WebApr 10, 2024 · The alpha-thalassemia mental retardation X-linked (ATRX) syndrome protein is a chromatin remodeling protein that primarily promotes the deposit of H3.3 histone … WebDec 1, 2024 · PDF Background: Misregulation of the p53-mdm2 loop function is a major mechanism to promote hepatocellular carcinoma (HCC). RBM38, a member of the... …
Rbm38 in cancer: role and mechanism
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WebOct 25, 2011 · RBM38 in cancer: role and mechanism. 08 July 2024. Cheng Zou, Ying Wan, ... and wt p53 status, suggesting a tumour suppressive role of RBM38 in breast cancer . ... WebThe RNA-binding protein Rbm38 is dispensable during ... Somatic mutational landscape of splicing factor genes and their functional consequences across 33 Cancer types. Cell Rep. 2024; 23: 282 ... a subset of patients with end-stage heart failure may represent a starting point for future studies to elucidate their role and mechanism in the ...
WebJul 8, 2024 · Here, we review the evidence that RBM38, an intensively studied RBP, frequently plays a tumor-suppressive role in multiple human cancer types. Genetic studies … WebApr 8, 2024 · Extrachromosomal circular DNAs (eccDNAs) participate in tumorigenesis and tumor progression. However, the role and mechanism of eccDNAs have yet to be elucidated in non-small cell lung cancer (NSCLC).
WebInternational Journal of Molecular Sciences, an international, peer-reviewed Open Access journal. WebApr 11, 2024 · Moreover, specific inhibitors of c-Myc transcriptional activity inhibited RBM38-induced suppression of growth, implying that RBM38 acts as a tumor suppressor …
WebAug 22, 2024 · Breast cancer is the most common malignancy in females worldwide (Chen et al, 2016; Siegel et al, 2016), and the metastasis accounts for the majority of deaths from breast cancer.One potential mechanism for invasion and metastasis in breast cancer is due to the occurring of epithelial–mesenchymal transition (EMT) that allows the polarised …
WebHepatocellular carcinoma (HCC) is the most common type of liver cancer in China, and the development and progression of HCC is a complex pathological process. As a new way of cell death, ferroptosis has huge potential in the treatment of HCC. This article introduces the mechanism of action of the tumor suppressor p53 in regulating ferroptosis and briefly … raymond eugene brown in marylandWebDec 15, 2014 · Too much Rbm38 reduces p53 levels, increasing the risk of cancer. Too little Rbm38 allows p53 overexpression, causing premature aging. The study was published in the journal PNAS on Dec. 15. "The ... simplicity sw210 denim star sewing machinehttp://lcgdbzz.org/en/article/doi/10.3969/j.issn.1001-5256.2024.04.032 simplicity sunstar mower deck partsWebSep 29, 2011 · This review highlights a decade of investigations into the role of CD38 in CLL. An association between CD38 expression by CLL cells and a more aggressive clinical behavior was first reported in 1999 4 and confirmed by several subsequent studies. 8-12 Consequently, determination of the percentage of CD38-expressing cells within a clone … raymond evans facebookWebCROSS-REFERENCE TO RELATED APPLICATIONS. This application is a Continuation of U.S. patent application Ser. No. 16/649,732, filed Mar. 23, 2024, which is a national stage filing u simplicity svqs ltdWebJul 8, 2024 · The evidence that RBM38, an intensively studied RBP, frequently plays a tumor-suppressive role in multiple human cancer types is reviewed and the possibility of … raymond eversden constructionWebHepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. Recent studies reported that lncRNA LINC00473 (LNC473) was involved in cancer progression. However, the clinical significance and functional role of LNC473 in HCC progression is still unknown. In the present study, we found that the LNC473 expression ... raymond eugene white